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Article

Integrated genomic and transcriptomic analysis of ductal carcinoma in situ of the breast.

Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Apr 2008

Vincent-Salomon Anne, Lucchesi Carlo, Gruel Nadège, Raynal Virginie, Pierron Gaëlle, Goudefroye Rémi, Reyal Fabien, Radvanyi François, Salmon Rémy, Thiery Jean-Paul, Sastre-Garau Xavier, Sigal-Zafrani Brigitte, Fourquet Alain, Delattre Olivier

Abstract excerpt

PURPOSE: To gain insight into genomic and transcriptomic subtypes of ductal carcinomas in situ of the breast (DCIS). EXPERIMENTAL DESIGN: We did a combined phenotypic and genomic analysis of a series of 57 DCIS integrated with gene expression profile analysis for 26 of the 57 cases. RESULTS: Thirty-two DCIS exhibited a luminal phenotype; 21 were ERBB2 positive, and 4 were ERBB2/estrogen receptor (ER) negative...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 18381933
DOI: 10.1158/1078-0432.CCR-07-1465

Genes

ERBB2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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