Article
Molecular genetic anatomy of inter- and intraserotype variation in the human bacterial pathogen group A Streptococcus.
Proceedings of the National Academy of Sciences of the United States of America - 2 May 2006
Beres Stephen B, Richter Ellen W, Nagiec Michal J, Sumby Paul, Porcella Stephen F, DeLeo Frank R, Musser James M
Abstract excerpt
In recent years we have studied the relationship between strain genotypes and patient phenotypes in group A Streptococcus (GAS), a model human bacterial pathogen that causes extensive morbidity and mortality worldwide. We have concentrated our efforts on serotype M3 organisms because these strains are common causes of pharyngeal and invasive infections, produce unusually severe invasive infections, and can...
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