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Article

Evolutionary origin and emergence of a highly successful clone of serotype M1 group a Streptococcus involved multiple horizontal gene transfer events.

The Journal of infectious diseases - 1 Sept 2005

Sumby Paul, Porcella Steve F, Madrigal Andres G, Barbian Kent D, Virtaneva Kimmo, Ricklefs Stacy M, Sturdevant Daniel E, Graham Morag R, Vuopio-Varkila Jaana, Hoe Nancy P, Musser James M

Abstract excerpt

To better understand the molecular events involved in the origin of new pathogenic bacteria, we studied the evolution of a highly virulent clone of serotype M1 group A Streptococcus (GAS). Genomic, DNA-DNA microarray, and single-nucleotide polymorphism analyses indicated that this clone evolved through a series of horizontal gene transfer events that involved (1) the acquisition of prophages encoding...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Identifiers

PMID: 16088826
DOI: 10.1086/432514

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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