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Article

The Role of Conformational Dynamics and Allostery in the Disease Development of Human Ferritin.

Biophysical journal - 15 Sept 2015

Kumar Avishek, Glembo Tyler J, Ozkan S Banu

Abstract excerpt

Determining the three-dimensional structure of myoglobin, the first solved structure of a protein, fundamentally changed the way protein function was understood. Even more revolutionary was the information that came afterward: protein dynamics play a critical role in biological functions. Therefore, understanding conformational dynamics is crucial to obtaining a more complete picture of protein evolution. We...

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Identifiers

PMID: 26255589
DOI: 10.1016/j.bpj.2015.06.060
PMCID: PMC4576160

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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