Infrequent TRIB3 coding variants and coronary artery disease in type 2 diabetes.

doi:10.1016/j.atherosclerosis.2015.07.030

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Article

Infrequent TRIB3 coding variants and coronary artery disease in type 2 diabetes.

Atherosclerosis - 1 Sept 2015

Prudente Sabrina, Bailetti Diego, Mendonca Christine, Mannino Gaia Chiara, Fontana Andrea, Andreozzi Francesco, Hastings Timothy, Mercuri Luana, Alberico Federica, Basile Giorgio, Copetti Massimiliano, Sesti Giorgio, Doria Alessandro, Trischitta Vincenzo

Abstract excerpt

OBJECTIVE: Genes that modulate insulin sensitivity may also be involved in shaping the risk of coronary artery disease (CAD). The relatively common TRIB3 Q84R polymorphism (rs2295490) has been associated with abnormal insulin signaling, endothelial dysfunction, insulin resistance, and pro-atherogenic phenotypes. The aim of our study was to investigate the association between low-frequency TRIB3 coding variants...

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Identifiers

PMID: 26253791
DOI: 10.1016/j.atherosclerosis.2015.07.030
PMCID: PMC4872508

Genes

TRIB3
CAD

Variants

rs2295490

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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