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Coronary artery disease patients with rs7904519 (TCF7L2) are at a persistent risk of type 2 diabetes.

Diabetes research and clinical practice - 1 Jan 2024

Al Hageh Cynthia, O'Sullivan Siobhan, Platt Daniel E, Henschel Andreas, Chacar Stephanie, Gauguier Dominique, Abchee Antoine, Alefishat Eman, Nader Moni, Zalloua Pierre A

Abstract excerpt

AIMS: Type 2 diabetes (T2D) and coronary artery disease (CAD) often coexist and share genetic factors.This study aimed to investigate the common genetic factors underlying T2D and CAD in patients with CAD. METHODS: A three-step association approach was conducted: a) a discovery step involving 943 CAD patients with T2D and 1,149 CAD patients without T2D; b) an eliminating step to exclude CAD or T2D specific...

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Share to Coronary Artery Disease
Share to Diabetes Mellitus, Type 2

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Genetic Loci

Share to Genetic Predisposition to Disease

Share to Polymorphism, Single Nucleotide

Share to Qb-SNARE Proteins

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Share to Transcription Factor 7-Like 2 Protein

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PMID: 38072013
DOI: 10.1016/j.diabres.2023.111052

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