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Trouble With Tribbles-1

25 Apr 2019

Abstract excerpt

Genome-wide association studies (GWAS) have identified hundreds of genomic loci in humans that are significantly associated with plasma cholesterol, triglycerides, and coronary artery disease. Although some loci contain genes with known regulatory roles in lipid metabolism and atherosclerosis, the majority were being implicated for the first time. The 8q24 locus, containing the gene TRIB1 ( Tribbles-1), is the...

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PMID: 31018662
DOI: 10.1161/atvbaha.118.311573

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