Article
Macrocyclic lactones and their relationship to the SNPs related to benzimidazole resistance.
Molecular and biochemical parasitology - 1 Jun 2015
Ashraf Shoaib, Mani Thangadurai, Beech Robin, Prichard Roger
Abstract excerpt
Haemonchus contortus is an abomasal nematode of ruminants that is widely present across the world. Its ability to cause death of infected animals and rapidly develop anthelmintic resistance makes it a dangerous pathogen. Ivermectin (IVM) and moxidectin (MOX) are macrocyclic lactones (MLs). They have been successfully used to treat parasitic nematodes over the last three decades. A genetic association between IVM...
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