Article
Two benzimidazole resistance-associated SNPs in the isotype-1 β-tubulin gene predominate in Haemonchus contortus populations from eight regions in China.
International journal for parasitology. Drugs and drug resistance - 1 Dec 2016
Zhang Zongze, Gasser Robin B, Yang Xin, Yin Fangyuan, Zhao Guanghui, Bao Min, Pan Baoliang, Huang Weiyi, Wang Chunren, Zou Fengcai, Zhou Yanqin, Zhao Junlong, Fang Rui, Hu Min
Abstract excerpt
Haemonchus contortus is one of the most important parasitic nematodes of small ruminants around the world, particularly in tropical and subtropical regions. The control of haemonchosis relies mainly on anthelmintics, but the excessive and prolonged use of anthelmintics is causing serious drug resistance issues in many countries. As benzimidazole (BZ) anthelmintics have been broadly used in China, we hypothesized...
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