Article
Single nucleotide polymorphism (SNP) markers for benzimidazole resistance in veterinary nematodes.
Parasitology - 1 Jan 2007
Von Samson-Himmelstjerna G, Blackhall W J, McCarthy J S, Skuce P J
Abstract excerpt
Resistance to the benzimidazole class of anthelmintics in nematodes of veterinary importance has a long history. Research into the mechanisms responsible for this resistance is subsequently at a more advanced stage than for other classes of anthelmintics. The principal mechanism of resistance to benzimidazoles is likely to involve changes in the primary structure of beta-tubulins, the building blocks of...
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