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GenBank-derived global inventory of benzimidazole resistance markers in the Haemonchus contortus β-tubulin 1 gene.

Molecular and biochemical parasitology - 1 Jun 2026

Azeem Abdullah, Khan Muhammad Kasib, Mehmood Muhammad Shahid, Abbas Rao Zahid, Ali Sultan, Mughal Muhammad Adnan Sabir, Abbas Zaheer, Afresham Sundas, Latif Mehroz, Imran Muhammad, Sindhu Zia Ud Din, Ashraf Muhammad Umer, Usman Muhammad, Ahmed Waqar

Abstract excerpt

Haemonchus contortus is a highly pathogenic gastrointestinal nematode of ruminants and a major cause of production losses in small livestock systems. Its rapid life cycle and blood-feeding habit make it one of the most damaging helminths affecting sheep and goats worldwide. Control relies mainly on anthelmintics, particularly benzimidazoles, macrocyclic lactones, and levamisole; however, resistance to these drug...

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PMID: 41956133
DOI: 10.1016/j.molbiopara.2026.111741

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