Article
Teladorsagia circumcincta beta tubulin: the presence of the E198L polymorphism on its own is associated with benzimidazole resistance.
Parasites & vectors - 7 Sept 2020
Martínez-Valladares María, Valderas-García Elora, Gandasegui Javier, Skuce Philip, Morrison Alison, Castilla Gómez de Agüero Verónica, Cambra-Pellejà Maria, Balaña-Fouce Rafael, Rojo-Vázquez Francisco A
Abstract excerpt
BACKGROUND: Benzimidazole resistance is associated with isotype-1 β-tubulin gene F200Y, E198A and F167Y SNPs. In this study, the recently described polymorphism E198L was reported and analysed in Teladorsagia circumcincta. METHODS: The benzimidazole phenotypic resistance was measured by the faecal egg count reduction test (FECRT) and the egg hatch test (EHT) using a discriminating dose (DD) in 39 sheep flocks....
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