Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Environmental Interactions and Epistasis Are Revealed in the Proteomic Responses to Complex Stimuli.

PloS one - 1 Jan 2015

Samir Parimal, Rahul, Slaughter James C, Link Andrew J

Abstract excerpt

Ultimately, the genotype of a cell and its interaction with the environment determine the cell's biochemical state. While the cell's response to a single stimulus has been studied extensively, a conceptual framework to model the effect of multiple environmental stimuli applied concurrently is not as well developed. In this study, we developed the concepts of environmental interactions and epistasis to explain the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Chromatography, High Pressure Liquid
Share to Epistasis, Genetic

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Glucose

Share to Glycerol

Share to Mass Spectrometry

Share to Proteome

Share to RNA, Messenger

Share to Saccharomyces cerevisiae

Source

Open in PubMed Open full text

Identifiers

PMID: 26247773
DOI: 10.1371/journal.pone.0134099
PMCID: PMC4527715

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Environmental Interactions and Epistasis Are Revealed in the Proteomic Responses to Complex Stimuli.PMID 26247773Read ↗

Environment-by-Environment Interactions Differ Across Genetic Backgrounds.Semantic proximity Read ↗

Genotype-by-environment interactions shape ubiquitin-proteasome system activity.Semantic proximity Read ↗

Gene by Environment Interactions reveal new regulatory aspects of signaling network plasticity.Semantic proximity Read ↗

Dominance vs. epistasis: the biophysical origins and plasticity of genetic interactions within and between allelesSemantic proximity Read ↗

A high-resolution gene expression atlas of epistasis between gene-specific transcription factors exposes potential mechanisms for genetic interactions.Semantic proximity Read ↗

Environmental robustness of the global yeast genetic interaction network.Semantic proximity Read ↗

Environment by environment interactions (ExE) differ across genetic backgrounds (ExExG)Semantic proximity Read ↗

Stochastic tuning of gene expression enables cellular adaptation in the absence of pre-existing regulatory circuitry.Semantic proximity Read ↗

Topology of protein interaction network shapes protein abundances and strengths of their functional and nonspecific interactions.Semantic proximity Read ↗

Dynamic genetic architecture of yeast response to environmental perturbation shed light on origin of cryptic genetic variation.Semantic proximity Read ↗

Integrator networks: illuminating the black box linking genotype and phenotype.Semantic proximity Read ↗

Environmental Regulation and Gene-by-Environment Interaction Influence <i>RAP1</i> Activity and its Impact on Gene ExpressionSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.