Article
A Defective Meiotic Outcome of a Failure in Homologous Pairing and Synapsis Is Masked by Meiotic Quality Control.
PloS one - 1 Jan 2015
Mei Frank, Chen Peter F, Dombecki Carolyn R, Aljabban Imad, Nabeshima Kentaro
Abstract excerpt
Successful gamete production is ensured by meiotic quality control, a process in which germ cells that fail in bivalent chromosome formation are eliminated during meiotic prophase. To date, numerous meiotic mutants have been isolated in a variety of model organisms, using defects associated with a failure in bivalent formation as hallmarks of the mutant. Presumably, the meiotic quality control mechanism in those...
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