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Article

Genetic and molecular characterization of the caenorhabditis elegans gene, mel-26, a postmeiotic negative regulator of mei-1, a meiotic-specific spindle component.

Genetics - 1 Sept 1998

Dow M R, Mains P E

Abstract excerpt

We have previously described the gene mei-1, which encodes an essential component of the Caenorhabditis elegans meiotic spindle. When ectopically expressed after the completion of meiosis, mei-1 protein disrupts the function of the mitotic cleavage spindles. In this article, we describe the cloning and the further genetic characterization of mel-26, a postmeiotic negative regulator of mei-1. mel-26 was originally...

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Identifiers

PMID: 9725834
DOI: 10.1093/genetics/150.1.119
PMCID: PMC1460337

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