Article
Inhibition of stationary phase respiration impairs persister formation in E. coli.
Nature communications - 6 Aug 2015
Orman Mehmet A, Brynildsen Mark P
Abstract excerpt
Bacterial persisters are rare phenotypic variants that temporarily tolerate high antibiotic concentrations. Persisters have been hypothesized to underlie the recalcitrance of biofilm infections, and strategies to eliminate these cells have the potential to improve treatment outcomes for many hospital-treated infections. Here we investigate the role of stationary phase metabolism in generation of type I persisters...
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