Article
Antibiotic exposure and recovery of persister states influence virulence phenotypes in Pseudomonas aeruginosa.
Archives of microbiology - 16 Jun 2026
da Cruz Nizer Waleska Stephanie, Igídio Carlos Eduardo Dias, Ribeiro Estela Mafra, Andrade Allanis Cristiny Oliveira, de Oliveira Samantha Neves, Teixeira Mauro Martins, de Souza Daniele da Glória, Fagundes Caio Tavares
Abstract excerpt
The pathogenicity of P. aeruginosa is not only mediated by its resistance mechanisms but also by its ability to form persister cells. The persister state is a transient condition in which cells retain a dormant, non- or slow-growing state during exposure to stressors, such as high doses of bactericidal antibiotics, but can resume growth once the stress is removed. In this study, we investigated in vitro the...
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