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Isolation and characterization of persisters of the pathogenic microorganism Staphylococcus aureus

16 May 2024

Abstract excerpt

The presence of antibiotic persisters is one of the leading causes of recurrent and chronic diseases. One challenge in mechanistic research on persisters is the enrichment of pure persisters. In this work, we validated a proposed method to isolate persisters with notorious Staphylococcus aureus cultures. With this, we analyzed the proteome profile of pure persisters and revealed the distinct mechanisms associated...

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PMID: 38868179
DOI: 10.1016/j.isci.2024.110002

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