Article
Host Cell Oxidative Stress Induces Dormant Staphylococcus aureus Persisters.
Microbiology spectrum - 23 Feb 2022
Peyrusson Frédéric, Nguyen Tiep Khac, Najdovski Tome, Van Bambeke Françoise
Abstract excerpt
Persisters are transiently nongrowing and antibiotic-tolerant phenotypic variants identified in major human pathogens, including intracellular Staphylococcus aureus. Due to their capacity to regrow once the environmental stress is relieved and to promote resistance, persisters possibly contribute to therapeutic failures. While persistence and its related quiescence have been mostly studied under starvation,...
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