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Article

Association of COMT and SLC6A3 polymorphisms with impulsivity, response inhibition and brain function.

Cortex; a journal devoted to the study of the nervous system and behavior - 1 Oct 2015

Kasparbauer Anna-Maria, Merten Natascha, Aichert Désirée S, Wöstmann Nicola, Meindl Thomas, Rujescu Dan, Ettinger Ulrich

Abstract excerpt

Evidence of the genetic correlates of inhibitory control is scant. Two previously studied dopamine-related polymorphisms, COMT rs4680 and the SLC6A3 3' UTR 40-base-pair VNTR (rs28363170), have been associated with response inhibition, however with inconsistent findings. Here, we investigated the influence of these two polymorphisms in a large healthy adult sample (N = 515) on a response inhibition battery...

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Source

Identifiers

PMID: 26245713
DOI: 10.1016/j.cortex.2015.07.002

Genes

COMT

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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