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Hierarchical investigation of genetic influences on response inhibition in healthy young adults.

Experimental and clinical psychopharmacology - 1 Dec 2017

Weafer Jessica, Gray Joshua C, Hernandez Kyle, Palmer Abraham A, MacKillop James, de Wit Harriet

Abstract excerpt

Poor inhibitory control is a known risk factor for substance use disorders, making it a priority to identify the determinants of these deficits. The aim of the current study was to identify genetic associations with inhibitory control using the stop signal task in a large sample (n = 934) of healthy young adults of European ancestry. We genotyped the subjects genome-wide and then used a hierarchical approach in...

Topics

Adolescent
Adult
Female
Genetic Association Studies
Genotype
Humans
Inhibition, Psychological
Male
Polymorphism, Single Nucleotide
Protein Serine-Threonine Kinases
Receptor, Serotonin, 5-HT2A

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Risk Factors

Substance-Related Disorders

White People

Young Adult

Source

Open in PubMed Open full text

Identifiers

PMID: 29251981
DOI: 10.1037/pha0000156
PMCID: PMC5737791

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

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