Predictors of contralateral prophylactic mastectomy in women with a BRCA1 or BRCA2 mutation: the Hereditary Breast Cancer Clinical Study Group.

doi:10.1200/JCO.2007.12.6078

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Article

Predictors of contralateral prophylactic mastectomy in women with a BRCA1 or BRCA2 mutation: the Hereditary Breast Cancer Clinical Study Group.

Journal of clinical oncology : official journal of the American Society of Clinical Oncology - 1 Mar 2008

Metcalfe Kelly A, Lubinski Jan, Ghadirian Parviz, Lynch Henry, Kim-Sing Charmaine, Friedman Eitan, Foulkes William D, Domchek Susan, Ainsworth Peter, Isaacs Claudine, Tung Nadine, Gronwald Jacek, Cummings Shelly, Wagner Teresa, Manoukian Siranoush, Møller Pål, Weitzel Jeffrey, Sun Ping, Narod Steven A

Abstract excerpt

PURPOSE: To evaluate the rate of prophylactic contralateral mastectomy in an international cohort of women with hereditary breast cancer and to evaluate the predictors of uptake of preventive surgery. PATIENTS AND METHODS: Women with a BRCA1 or BRCA2 mutation who had been diagnosed with unilateral breast cancer were followed prospectively for a minimum of 1.5 years. Information was collected on prophylactic...

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PMID: 18195327
DOI: 10.1200/JCO.2007.12.6078

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BRCA1
BRCA2

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