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Article

Suppression of intestinal carcinogenesis in Apc-mutant mice by limonin

1 Jan 2015

Abstract excerpt

Limonoids in citrus fruits are known to possess multiple biological functions, such as anti-proliferative functions in human cancer cell lines. Therefore, we aimed to investigate the suppressive effect of limonin on intestinal polyp development in Apc-mutant Min mice. Five-week-old female Min mice were fed a basal diet or a diet containing 250 or 500 ppm limonin for 8 weeks. The total number of polyps in mice...

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PMID: 26236099
DOI: 10.3164/jcbn.15-28

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