Article
Toward point-of-care testing for JAK2 V617F mutation on a microchip.
Journal of chromatography. A - 4 Sept 2015
Wang Hua, Liu Weiwei, Zhang Xinju, Xu Xiao, Kang Zhihua, Li Shibao, Wu Zhiyuan, Yang Zhiliu, Yao Bo, Guan Ming
Abstract excerpt
Molecular genetics now plays a crucial role in diagnosis, the identification of prognostic markers, and monitoring of hematological malignancies. Demonstration of acquired changes such as the JAK2 V617F mutation within myeloproliferative neoplasms (MPN) has quickly moved from a research setting to the diagnostic laboratory. Microfluidics-based assays can reduce the assay time and sample/reagent consumption and...
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