Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Variations in opioid receptor genes in neonatal abstinence syndrome.

Drug and alcohol dependence - 1 Oct 2015

Wachman Elisha M, Hayes Marie J, Sherva Richard, Brown Mark S, Davis Jonathan M, Farrer Lindsay A, Nielsen David A

Abstract excerpt

BACKGROUND: There is significant variability in the severity of neonatal abstinence syndrome (NAS) due to in-utero opioid exposure. We wanted to determine if single nucleotide polymorphisms (SNPs) in key candidate genes contribute to this variability. METHODS: Full-term opioid-exposed newborns and their mothers (n=86 pairs) were studied. DNA was genotyped for 80 SNPs from 14 genes utilizing a custom designed...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Catechol O-Methyltransferase
Share to Length of Stay

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Microarray Analysis

Share to Protein Precursors

Share to Receptors, Opioid

Share to Receptors, Opioid, delta

Share to Receptors, Opioid, kappa

Share to Receptors, Opioid, mu

Source

Open in PubMed Open full text

Identifiers

PMID: 26233486
DOI: 10.1016/j.drugalcdep.2015.07.001
PMCID: PMC4581974

Genes

PNOC
COMT
OPRD1
OPRK1
OPRM1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Variations in opioid receptor genes in neonatal abstinence syndrome.PMID 26233486Read ↗

Association of maternal and infant variants in PNOC and COMT genes with neonatal abstinence syndrome severity.Semantic proximity Read ↗

Epigenetic variation in OPRM1 gene in opioid‐exposed mother‐infant dyadsSemantic proximity Read ↗

Association of OPRM1 and COMT single-nucleotide polymorphisms with hospital length of stay and treatment of neonatal abstinence syndrome.Semantic proximity Read ↗

Epigenetic Variation in the Mu-Opioid Receptor Gene in Infants with Neonatal Abstinence SyndromeSemantic proximity Read ↗

Genetic determinants of fetal opiate exposure and risk of neonatal abstinence syndrome: Knowledge deficits and prospects for future research.Semantic proximity Read ↗

Overview of genetic analysis of human opioid receptors.Semantic proximity Read ↗

Overview of Genetic Analysis of Human Opioid Receptors.Semantic proximity Read ↗

Pharmacogenomic predictors of neonatal abstinence syndrome: correlation with length of stay.Semantic proximity Read ↗

Polygenic risk scores and the need for pharmacotherapy in neonatal abstinence syndrome.Semantic proximity Read ↗

Pharmacogenomics of the human µ-opioid receptor.Semantic proximity Read ↗

Identifying Opioid-Related Pharmacogenomic Variants in High-Risk Hospitalized Infants: A Pilot StudySemantic proximity Read ↗

Searching for evidence of genetic mediation of opioid withdrawal by opioid receptor gene polymorphisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.