Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Genetic determinants of fetal opiate exposure and risk of neonatal abstinence syndrome: Knowledge deficits and prospects for future research.

Clinical pharmacology and therapeutics - 1 Sept 2015

Lewis T, Dinh J, Leeder J S

Abstract excerpt

Opiate-dependent pregnant women receive opiate maintenance medications to prevent illicit use and withdrawal. Fetal opiate exposure causes central nervous system (CNS) alterations which manifest as postnatal physical withdrawal. The extensive variability in the Neonatal Abstinence Syndrome phenotype remains unexplained and may be related to variability in fetal exposure and response. Improved understanding of...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analgesics, Opioid
Share to Biotransformation

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Maternal Exposure

Share to Maternal-Fetal Exchange

Share to Opioid-Related Disorders

Share to Pharmacogenetics

Share to Prenatal Exposure Delayed Effects

Share to Tissue Distribution

Source

Open in PubMed Open full text

Identifiers

PMID: 26058918
DOI: 10.1002/cpt.159
PMCID: PMC5484056

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Genetic determinants of fetal opiate exposure and risk of neonatal abstinence syndrome: Knowledge deficits and prospects for future research.PMID 26058918Read ↗

Placental DNA methylation profiles in opioid-exposed pregnancies and associations with the neonatal opioid withdrawal syndromeSemantic proximity Read ↗

Epigenetic Variation in the Mu-Opioid Receptor Gene in Infants with Neonatal Abstinence SyndromeSemantic proximity Read ↗

The genetics and epigenetics of Neonatal Abstinence SyndromeSemantic proximity Read ↗

Variations in opioid receptor genes in neonatal abstinence syndrome.Semantic proximity Read ↗

Effect of Prenatal Opioid Exposure on the Human Placental MethylomeSemantic proximity Read ↗

Molecular and long-term behavioral consequences of neonatal opioid exposure and withdrawal in miceSemantic proximity Read ↗

Pharmacogenomic predictors of neonatal abstinence syndrome: correlation with length of stay.Semantic proximity Read ↗

Neonatal medications.Semantic proximity Read ↗

The genetics of the opioid system and specific drug addictions.Semantic proximity Read ↗

The epigenetic legacy of illicit drugs: developmental exposures and late-life phenotypesSemantic proximity Read ↗

Polygenic risk scores and the need for pharmacotherapy in neonatal abstinence syndrome.Semantic proximity Read ↗

Genetic Determinants of Addiction to Opioids and CocaineSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.