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Article

Epigenetic variation in OPRM1 gene in opioid‐exposed mother‐infant dyads

25 Mar 2018

Abstract excerpt

Neonatal abstinence syndrome (NAS) due to in-utero opioid exposure has significant variability of severity. Preliminary studies have suggested that epigenetic variation within the μ-opioid receptor (OPRM1) gene impacts NAS. We aimed to determine if DNA methylation in OPRM1 within opioid-exposed mother-infant dyads is associated with differences in NAS severity in an independent cohort. Full-term opioid-exposed...

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PMID: 29575474
DOI: 10.1111/gbb.12476

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