Article

Identifying Opioid-Related Pharmacogenomic Variants in High-Risk Hospitalized Infants: A Pilot Study

2024-10-27

Abstract excerpt

<h4>Introduction</h4> Pharmacogenomic (PGx) variants impact the pharmacodynamics and pharmacokinetics of opioids and the brain’s reward, cognition, stress, and pain pathways. This study examines the prevalence of PGx variants impacting opioid response among a cohort of high-risk infants. <h4>Methods</h4> This retrospective study was conducted at a quaternary children’s hospital from 2009-2020. Infants <1y with ≥1...

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Literature Corpus work: 5e17bda4-2511-5b2e-8fe1-d84ee74d2bcf
DOI: 10.1101/2024.10.25.24316140

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