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Article

Reducing the search space for causal genetic variants with VASP.

Bioinformatics (Oxford, England) - 15 Jul 2015

Field Matthew A, Cho Vicky, Cook Matthew C, Enders Anselm, Vinuesa Carola G, Whittle Belinda, Andrews T Daniel, Goodnow Chris C

Abstract excerpt

MOTIVATION: Increasingly, cost-effective high-throughput DNA sequencing technologies are being utilized to sequence human pedigrees to elucidate the genetic cause of a wide variety of human diseases. While numerous tools exist for variant prioritization within a single genome, the ability to concurrently analyze variants within pedigrees remains a challenge, especially should there be no prior indication of the...

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Identifiers

PMID: 25755272
DOI: 10.1093/bioinformatics/btv135
PMCID: PMC4495293

Genes

VASP

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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