Article
Selecting single-nucleotide polymorphisms for association studies with SNPbrowser software.
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2007
De La Vega Francisco M
Abstract excerpt
The design of genetic association studies using single-nucleotide polymorphisms (SNPs) requires the selection of subsets of the variants providing high statistical power at a reasonable cost. SNPs must be selected to maximize the probability that a causative mutation is in linkage disequilibrium (LD) with at least one marker genotyped in the study. The HapMap Project performed a genome-wide survey of genetic...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.