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Article

Familial Longevity Is Associated With Higher TSH Secretion and Strong TSH-fT3 Relationship

31 Jul 2015

Abstract excerpt

CONTEXT: Longevity is associated with changes in circulating levels of thyroid hormone (TH) and/or TSH in animals and humans, but underlying mechanisms remain elusive. OBJECTIVE: We explored in 38 offspring of nonagenarian participants from the Leiden Longevity Study, who are enriched for longevity and in their partners, ultradian and circadian rhythmicity of TSH, temporal relationship, and feedback and forward...

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PMID: 26230295
DOI: 10.1210/jc.2015-2624

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