Article
Familial longevity is associated with decreased thyroid function.
The Journal of clinical endocrinology and metabolism - 1 Nov 2010
Rozing M P, Houwing-Duistermaat J J, Slagboom P E, Beekman M, Frölich M, de Craen A J M, Westendorp R G J, van Heemst D
Abstract excerpt
CONTEXT: A relation between low thyroid activity and prolonged life span in humans has been observed. Several studies have demonstrated hereditary and genetic influences on thyroid function. OBJECTIVE: The objective of the study was to test whether low thyroid activity associated with extreme longevity constitutes a heritable phenotype, which could contribute to the familial longevity observed in the Leiden...
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