Article
Genetic predisposition to elevated serum thyrotropin is associated with exceptional longevity.
The Journal of clinical endocrinology and metabolism - 1 Dec 2009
Atzmon Gil, Barzilai Nir, Surks Martin I, Gabriely Ilan
Abstract excerpt
CONTEXT: Exceptional longevity is associated with raised serum TSH. OBJECTIVE: The aim of this study was to examine whether offspring of people with exceptional longevity have elevated serum TSH and whether specific single nucleotide polymorphisms (SNPs) in the TSH-B gene and TSH receptor (TSHR) gene are associated with this phenotype. DESIGN/SETTING/PATIENTS: We measured serum TSH and free T(4) in Ashkenazi...
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