Article
Familial longevity is characterized by high circadian rhythmicity of serum cholesterol in healthy elderly individuals
19 Nov 2016
Abstract excerpt
The biological clock, whose function deteriorates with increasing age, determines bodily circadian (i.e. 24h) rhythms, including that of cholesterol metabolism. Dampening of circadian rhythms has been associated with aging and disease. Therefore, we hypothesized that individuals with a familial predisposition for longevity have a higher amplitude circadian serum cholesterol concentration rhythm. The aim of this...
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