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Article

Susceptibility loci for heroin and cocaine addiction in the serotonergic and adrenergic pathways in populations of different ancestry.

Pharmacogenomics - 1 Jan 2015

Levran Orna, Peles Einat, Randesi Matthew, Correa da Rosa Joel, Ott Jurg, Rotrosen John, Adelson Miriam, Kreek Mary Jeanne

Abstract excerpt

BACKGROUND: Drug addiction is influenced by genetic factors. AIM: To determine if genetic variants in the serotonergic and adrenergic pathways are associated with heroin and/or cocaine addiction. SUBJECTS & METHODS: The study examined 140 polymorphisms in 19 genes in 1855 subjects with predominantly European or African ancestries. RESULTS: A total of 38 polymorphisms (13 genes) showed nominal associations,...

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Identifiers

PMID: 26227246
DOI: 10.2217/pgs.15.86
PMCID: PMC4896084

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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