Article
Genotype patterns that contribute to increased risk for or protection from developing heroin addiction.
Molecular psychiatry - 1 Apr 2008
Nielsen D A, Ji F, Yuferov V, Ho A, Chen A, Levran O, Ott J, Kreek M J
Abstract excerpt
A genome-wide association study was conducted using microarray technology to identify genes that may be associated with the vulnerability to develop heroin addiction, using DNA from 104 individual former severe heroin addicts (meeting Federal criteria for methadone maintenance) and 101 individual control subjects, all Caucasian. Using separate analyses for autosomal and X chromosomal variants, we found that the...
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