Differential role of serotonergic polymorphisms in alcohol and heroin dependence.

doi:10.1016/j.pnpbp.2009.03.016

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Article

Differential role of serotonergic polymorphisms in alcohol and heroin dependence.

Progress in neuro-psychopharmacology & biological psychiatry - 15 Jun 2009

Saiz Pilar A, Garcia-Portilla Maria P, Florez Gerardo, Arango Celso, Corcoran Paul, Morales Blanca, Bascaran Maria-Teresa, Alvarez Cesar, San Narciso Gema, Carreño Eduardo, Alvarez Victoria, Coto Eliecer, Bobes Julio

Abstract excerpt

BACKGROUND: Twin studies suggest that genetic factors account for 40-60% of the variance in alcohol dependence. It has been stated that different drug dependencies may have unique genetic influences. Alterations in serotonin availability and function can affect drinking behaviour. This study aimed to investigate whether three serotonergic polymorphisms (HTR2A A-1438G (rs6311), and SCL6A4 5-HTTLPR and STin2 VNTR)...

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Identifiers

PMID: 19328219
DOI: 10.1016/j.pnpbp.2009.03.016

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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