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Article

PPAR gamma variant influences angiographic outcome and 10-year cardiovascular risk in male symptomatic coronary artery disease patients.

Diabetes care - 1 May 2009

Regieli Jakub J, Jukema J Wouter, Doevendans Pieter A, Zwinderman Aeilko H, van der Graaf Yolanda, Kastelein John J, Grobbee Diederick E

Abstract excerpt

OBJECTIVE: Activation of peroxisome proliferator-activated receptor (PPAR)-gamma signaling influences metabolic profiles and the propensity toward inflammation. Small-molecule stimulation of PPARgamma is investigated for secondary prevention of cardiovascular disease. The common PPARgamma Pro12Ala variant has functional and prognostic consequences. A protective effect of the 12Ala-allele carriership on diabetes...

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Identifiers

PMID: 19228871
DOI: 10.2337/dc08-1819
PMCID: PMC2671091

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CAD

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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