Article
Polymorphism in miRNA-1 target site and circulating miRNA-1 phenotype are associated with the decreased risk and prognosis of coronary artery disease.
International journal of clinical and experimental pathology - 1 Jan 2014
Wang Lina, Zhi Hong, Li Yongjun, Ma Genshan, Ye Xingzhou, Yu Xiaojin, Yang Tian, Jin Han, Lu Zuhong, Wei Pingmin
Abstract excerpt
MiRNA molecules have been identified to play key roles in a broad range of physiologic and pathologic processes. Polymorphisms in microRNA target sites (PolymiRTSs) can disturb or obstruct miRNA binding and consequentially influence regulation of the target genes. A two-step study design was used in this study. A case-control study was designed to assess the relationship between miRNA-1 target site rs9548934C→T...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
