Article
Polymorphisms in advanced glycosylation end product-specific receptor (AGER) gene, insulin resistance, and type 2 diabetes mellitus.
Clinica chimica acta; international journal of clinical chemistry - 1 Dec 2008
Goulart A C, Germer S, Rexrode K M, Martin M, Zee R Y L
Abstract excerpt
BACKGROUND: Variants in the advanced glycosylation end product-specific receptor (AGER) gene have been associated with diabetic vasculopathy, however their role in the pathogenesis of insulin resistance and type 2 diabetes mellitus (T2DM) are uncertain. We investigated the relationship of 3 polymorphisms (rs1800625, rs1800624 and rs2070600) in the AGER gene and their haplotypes with T2DM as well as insulin...
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