Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Global DNA methylation changes and differential gene expression in Anaplasma phagocytophilum-infected human neutrophils

28 Jul 2015

Abstract excerpt

BACKGROUND: Anaplasma phagocytophilum is an obligate intracellular prokaryotic pathogen that both infects and replicates within human neutrophils. The bacterium represses multiple antimicrobial functions while simultaneously increasing proinflammatory functions by reprogramming the neutrophil genome. Previous reports show that many observed phenotypic changes are in part explained by altered gene transcription....

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Amoebic Infections and Treatments
Share to Reproductive tract infections research
Share to Vector-borne infectious diseases

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26225157
DOI: 10.1186/s13148-015-0105-1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 8 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Global DNA methylation changes and differential gene expression in Anaplasma phagocytophilum-infected human neutrophilsPMID 26225157Read ↗

Lessons from Anaplasma phagocytophilum: Chromatin Remodeling by Bacterial EffectorsSemantic proximity Read ↗

An O-Methyltransferase Is Required for Infection of Tick Cells by Anaplasma phagocytophilumSemantic proximity Read ↗

Global Transcription Profiles of Anaplasma phagocytophilum at Key Stages of Infection in Tick and Human Cell Lines and GranulocytesSemantic proximity Read ↗

Bacterial Infection Remodels the DNA Methylation Landscape of Human Dendritic CellsSemantic proximity Read ↗

Bioinformatic and mass spectrometry identification of Anaplasma phagocytophilum proteins translocated into host cell nucleiSemantic proximity Read ↗

DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenesSemantic proximity Read ↗

Integrative profiling of early host chromatin accessibility responses in human neutrophils with sensitive pathogen detectionSemantic proximity Read ↗

DNA Methylation by Restriction Modification Systems Affects the Global Transcriptome Profile in <i>Borrelia burgdorferi</i>Semantic proximity Read ↗

Pathogenic mechanisms of intracellular bacteriaSemantic proximity Read ↗

Exposure to extracellular vesicles from Pseudomonas aeruginosa result in loss of DNA methylation at enhancer and DNase hypersensitive site regions in lung macrophagesSemantic proximity Read ↗

AamA-mediated epigenetic control of genome-wide gene expression and phenotypic traits in Acinetobacter baumannii ATCC 17978.Semantic proximity Read ↗

The emerging role of DNA methylation in the pathogenicity of bacterial pathogensSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.