Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Topics Community

Article

AamA-mediated epigenetic control of genome-wide gene expression and phenotypic traits in Acinetobacter baumannii ATCC 17978.

Microbial genomics - 1 Aug 2023

Yang Jihye, Son Yongjun, Kang Mingyeong, Park Woojun

Abstract excerpt

Individual deletions of three genes encoding orphan DNA methyltransferases resulted in the occurrence of growth defect only in the aamA (encoding AcinetobacterAdenine Methylase A) mutant of A. baumannii strain ATCC 17978. Our single-molecule real-time sequencing-based methylome analysis revealed multiple AamA-mediated DNA methylation sites and proposed a potent census target motif (TTTRAATTYAAA). Loss of Dam led...

Topics

Acinetobacter baumannii
Epigenesis, Genetic
Epigenome
Phenotype
Gene Expression

Source

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Identifiers

PMID: 37589545
DOI: 10.1099/mgen.0.001093
PMCID: PMC10483419

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 31 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

AamA-mediated epigenetic control of genome-wide gene expression and phenotypic traits in Acinetobacter baumannii ATCC 17978.PMID 37589545Read ↗

The emerging role of DNA methylation in the pathogenicity of bacterial pathogensSemantic proximity Read ↗

Comparative Analysis of Whole-Genome and Methylome Profiles of a Smooth and a Rough Mycobacterium abscessus Clinical Strain.Semantic proximity Read ↗

Identification of a Pseudomonas aeruginosa PAO1 DNA Methyltransferase, Its Targets, and Physiological RolesSemantic proximity Read ↗

Epigenetic regulation in prokaryotes: transcriptional and phenotypic outcomes of DNA methyltransferase activity.Semantic proximity Read ↗

DNA methylation epigenetically regulates gene expression in <i>Burkholderia cenocepacia</i>Semantic proximity Read ↗

The tRNA methyltransferase TrmB is critical for Acinetobacter baumannii stress responses and pulmonary infectionSemantic proximity Read ↗

Role of DNA methyltransferases in epigenetic regulation in bacteria.Semantic proximity Read ↗

Expansion of the aminoglycoside-resistance 16S rRNA (m1A1408) methyltransferase family: Expression and functional characterization of four hypothetical enzymes of diverse bacterial originSemantic proximity Read ↗

DNA Methyltransferase HsdM Induce Drug Resistance on Mycobacterium tuberculosis via Multiple EffectsSemantic proximity Read ↗

Ribosomal A site binding pattern differs between Arm methyltransferases from clinical pathogens and a natural producer of aminoglycosides.Semantic proximity Read ↗

Aminoglycoside Resistance by ArmA-mediated Ribosomal 16S Methylation in Human Bacterial PathogensSemantic proximity Read ↗

DNA methylation from a Type I restriction modification system influences gene expression and virulence in Streptococcus pyogenesSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.