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Lessons from Anaplasma phagocytophilum: Chromatin Remodeling by Bacterial Effectors

1 Nov 2012

Abstract excerpt

Bacterial pathogens can alter global host gene expression via histone modifications and chromatin remodeling in order to subvert host responses, including those involved with innate immunity, allowing for bacterial survival. Shigella flexneri, Listeria monocytogenes, Chlamydia trachomatis, and Anaplasma phagocytophilum express effector proteins that modify host histones and chromatin structure. A. phagocytophilum...

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PMID: 23082961
DOI: 10.2174/187152612804142242

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