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An O-Methyltransferase Is Required for Infection of Tick Cells by Anaplasma phagocytophilum

6 Nov 2015

Abstract excerpt

Anaplasma phagocytophilum, the causative agent of Human Granulocytic Anaplasmosis (HGA), is an obligately intracellular α-proteobacterium that is transmitted by Ixodes spp ticks. However, the pathogen is not transovarially transmitted between tick generations and therefore needs to survive in both a mammalian host and the arthropod vector to complete its life cycle. To adapt to different environments, pathogens...

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PMID: 26544981
DOI: 10.1371/journal.ppat.1005248

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