Article
Prognostic significance of The Wilms' Tumor-1 (WT1) rs16754 polymorphism in acute myeloid leukemia.
Leukemia research - 1 Apr 2018
Petiti Jessica, Rosso Valentina, Lo Iacono Marco, Calabrese Chiara, Signorino Elisabetta, Gaidano Valentina, Berger Massimo, Saglio Giuseppe, Cilloni Daniela
Abstract excerpt
Acute myeloid leukemia is a genetically heterogeneous disease characterized by the accumulation of mutations in hematopoietic progenitor cells. For its heterogeneity, prognostic markers are very useful for therapeutic choice. The most important prognostic markers are age, white blood cell count, chromosomal alterations and gene mutations. Recent works have studied the prognostic significance of WT1 polymorphisms...
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