The Wilms Tumor-1 (WT1) rs2234593 variant is a prognostic factor in normal karyotype acute myeloid leukemia.

doi:10.1007/s00277-015-2534-5

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Article

The Wilms Tumor-1 (WT1) rs2234593 variant is a prognostic factor in normal karyotype acute myeloid leukemia.

Annals of hematology - 1 Jan 2016

Niavarani Ahmadreza, Horswell Stuart, Sadri Ramin, Bonnet Dominique

Abstract excerpt

The single-nucleotide polymorphism (SNP) within Wilms tumor-1 (WT1) exon 7, rs16754, has been arguably reported to be implicated in acute myeloid leukemia (AML) prognosis. We assessed the potential association of selected WT1 SNPs as well as WT1 mutations in normal karyotype (NK)-AML and evaluated the prognostic value of these normal gene variants. Diagnostic samples from a series of 474 young adult NK-AML...

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PMID: 26499507
DOI: 10.1007/s00277-015-2534-5

Genes

FLT3
NPM1

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