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Article

Attenuated humoral responses in HLA-A*24-positive individuals at risk of type 1 diabetes.

Diabetologia - 1 Oct 2015

Ye Jody, Long Anna E, Pearson James A, Taylor Hazel, Bingley Polly J, Williams Alistair J K, Gillespie Kathleen M

Abstract excerpt

AIMS/HYPOTHESIS: The rate of progression from islet autoimmunity to clinical type 1 diabetes depends on the rate of beta cell destruction. The HLA-A*24 gene is associated with early diabetes onset, but previous studies have shown attenuated humoral responses to islet antigens in individuals with both recent and long-standing type 1 diabetes carrying HLA-A*24. We aimed to establish whether HLA-A*24 is also...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 26224099
DOI: 10.1007/s00125-015-3702-9

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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Attenuated humoral responses in HLA-A*24-positive individuals at risk of type 1 diabetes.PMID 26224099Read ↗

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