Article
Humoral responses to islet antigen-2 and zinc transporter 8 are attenuated in patients carrying HLA-A*24 alleles at the onset of type 1 diabetes.
Diabetes - 1 Jun 2013
Long Anna E, Gillespie Kathleen M, Aitken Rachel J, Goode Julia C, Bingley Polly J, Williams Alistair J K
Abstract excerpt
The HLA-A*24 allele has shown negative associations with autoantibodies to islet antigen-2 (IA-2) and zinc transporter 8 (ZnT8) in patients with established type 1 diabetes. Understanding how this HLA class I allele affects humoral islet autoimmunity gives new insights into disease pathogenesis....
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