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Article

Novel Association Between Immune-Mediated Susceptibility Loci and Persistent Autoantibody Positivity in Type 1 Diabetes.

Diabetes - 1 Aug 2015

Brorsson Caroline A, Onengut Suna, Chen Wei-Min, Wenzlau Janet, Yu Liping, Baker Peter, Williams Alistair J K, Bingley Polly J, Hutton John C, Eisenbarth George S, Concannon Patrick, Rich Stephen S, Pociot Flemming

Abstract excerpt

Islet autoantibodies detected at disease onset in patients with type 1 diabetes are signs of an autoimmune destruction of the insulin-producing β-cells. To further investigate the genetic determinants of autoantibody positivity, we performed dense immune-focused genotyping on the Immunochip array...

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Topics

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Share to Autoantibodies
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Diabetes Mellitus, Type 1

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Source

Open in PubMed Open full text

Identifiers

PMID: 25829454
DOI: 10.2337/db14-1730
PMCID: PMC4512221

Genes

FCRL3
IFIH1
LPP
RELA

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-25829454-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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