Article
Neural Markers in Pediatric Bipolar Disorder and Familial Risk for Bipolar Disorder.
Journal of the American Academy of Child and Adolescent Psychiatry - 1 Jan 2017
Wiggins Jillian Lee, Brotman Melissa A, Adleman Nancy E, Kim Pilyoung, Wambach Caroline G, Reynolds Richard C, Chen Gang, Towbin Kenneth, Pine Daniel S, Leibenluft Ellen
Abstract excerpt
OBJECTIVE: Bipolar disorder (BD) is highly heritable. Neuroimaging studies comparing unaffected youth at high familial risk for BD (i.e., those with a first-degree relative with the disorder; termed "high-risk" [HR]) to "low-risk" (LR) youth (i.e., those without a first-degree relative with BD) and to patients with BD may help identify potential brain-based markers associated with risk (i.e., regions where...
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